LiMa project
The current project has a main focus, to decipher new biomarkers and/or novel targets to prevent visceral white adipose tissue exhaustion; a critical step in the etiology of the disease characterized by metabolic dysfunction, low grade chronic inflammation, and tissue fibrosis. Aimed to identify the key metabolic pathways, metabolites and regulatory genes contributing to the re-establishment of whole-body glucose homeostasis and beta-cell function in an animal model of T2D before and after a lifestyle intervention program. Prevention of visceral adipose tissue exhaustion is a strategic therapeutic approach as an early or preventive treatment of obesity, with the aim to delay nonalcoholic fatty liver disease (NAFLD) progression and obesity associated pathologies.
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The role of skeletal muscle respiratory capacity in exercise performance
The connection between the respiratory capacity of skeletal muscle mitochondria and athletic performance is widely acknowledged in contemporary research
The role of skeletal muscle respiratory capacity in exercise performance
The review proposes integrative strategies—targeting chrono-nutrition, sleep quality, and exercise timing—to align lifestyle behaviors with circadian biology, thereby preserving muscle health and improving overall metabolic outcomes.
L-Ergothioneine Attenuates Nephrolithiasis by Modulating Redox Signaling and Mitochondrial Function in Cystine and Calcium Oxalate Models
By targeting oxidative stress and mitochondrial dysfunction, l-Erg represents a promising therapeutic strategy for nephrolithiasis, either alone or as an adjunct to current treatments
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